By Kenneth A. Bock MD on December 27, 2010

Autism, ADHD, Asthma and Allergies: What’s Going on With Our Kids?

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I want to begin my first post here by talking about something that is very basic to the perpetuation of our society: our children. The specific question I want to ask is simple but key: What the heck is happening to our kids? Why am I starting with this question? Let me give you some background information.

In the United States and other industrialized, developed nations, epidemics of malnutrition and common childhood infectious illnesses are almost a thing of the past due primarily to the technological advances of our industrial era. However, we are in the midst of a group of new childhood epidemics that are directly related to this same industrialism and its associated pollution, environmental degradation and toxicity. One set of epidemics has, unfortunately, been replaced by another.

I have termed the new childhood epidemics “the 4-A disorders,” and they include autism, attention deficit hyperactivity disorder (ADHD), asthma and allergies. Over the past quarter of a century, autism has increased a staggering 1500 percent, while ADHD, asthma and allergies have also skyrocketed. I find these meteoric increases staggering, and they beg the question: Why?

This simultaneous rise is not coincidental. All of these disorders appear to be linked together by a similar mechanism: an underlying genetic vulnerability, triggered by environmental insults. The primary underlying genetic vulnerability appears to be, in many children, an impaired ability to detoxify, which has left them unable to cope with the ever increasing number and level of toxins to which they are exposed. These toxins include numerous chemicals, plasticizers, bisphenol A (BPA) and phthalates, flame retardants such as polybrominated diphenyl ethers (PBDE), polychlorinated biphenyls (PCBs), and pesticides such as organophosphates and organochlorines. They also include heavy metals, such as lead, arsenic, mercury, cadmium and aluminum. Added concerns arise from the phenomenon of synergistic toxicity among heavy metals and toxic chemicals. This means that even when threshold levels of individual toxins have not been exceeded, their combined effect can be quite significant and harmful.

To effectively overcome the inflammation, nutritional deficiencies, immune dysfunction and other disparate factors that often result in a diagnosis of one of the 4-A disorders, a comprehensive treatment program must be initiated. I call this the 4-A Healing Program, and it consists of five primary elements: avoiding toxicants, dietary modification, nutritional supplementation, detoxification and administration of medication (as appropriate).

Avoidance of toxicants is essential to nutritional and detoxification strategies, as they are obviously hampered by continued toxic environmental exposures. To explain this a bit further, let’s take the classic example of two people in a rowboat that has sprung a leak. One approach to the problem is to use a pail to bale the water out, working feverishly just to keep up with the water still coming in from the leak. On the other hand, they could plug the leak and prevent more water from coming in and thereby lessen the demand for corrective measures downstream. The second approach, plugging the leak, is what we’re doing by avoiding further exposures to environmental toxins.

Dietary modification is extremely important. Many children with 4-A disorders have gastrointestinal (GI) symptoms, including constipation, diarrhea, abdominal bloating, gas and pain. Most of those with GI symptoms (and even some without obvious GI symptoms) have underlying gut issues including malabsorption, maldigestion, dysbiosis (or unbalanced intestinal flora) and/or increased intestinal permeability – the so-called “leaky gut.” Main contributors to these gastrointestinal abnormalities are dietary factors, including food allergies, sensitivities and intolerances. The most common offending foods seem to be gluten (the protein in grains including wheat, barley, rye and some oats) and casein (a protein in dairy foods, including milk, cheese, yogurt and ice cream). Some of these foods may even promote an addictive-type effect due to the endogenous morphines they produce. Avoiding these foods, especially gluten and casein, may initially produce withdrawal symptoms but often ultimately results in significant positive changes.

Nutritional supplementation is virtually always needed to support healing. Most children with 4-A disorders suffer from significant nutritional deficiencies, which not only contribute to neurological dysfunction, but also to other metabolic processes, such as proper function of the body and brain. At times there are frank deficiencies, but in other instances there are nutrient insufficiencies and/or imbalances that can cause adverse effects. Because there is a significant overlap in the factors that cause the 4-A disorders, there is also often a significant overlap in the nutritional supplement programs that benefit the children suffering from these new childhood epidemics. Many of these children, regardless of their diagnoses, benefit from minerals (such as magnesium, zinc, selenium, chromium and iron), antioxidant vitamins (including vitamin A, vitamin C and vitamin E), the B vitamins, vitamin B-6 and methylcobalamin, vitamin D, targeted amino acids, essential fatty acids and probiotics.

Detoxification, the essential process of eliminating toxins from the body, can be significantly improved in many children, particularly those who suffer from impaired detoxification abilities. Methods for improving detoxification include the use of nutritional and herbal substances, including glutathione, taurine and curcumin, and in some cases the careful and judicious use of pharmaceutical chelators.

Medication, the fifth and final element of the program, is an integral part of treatment for many children who suffer from these disorders, and it is obviously an important factor in controlling asthma. In all of the 4-A disorders, a wide variety of medications may be of value, depending upon the individual needs of the child. These can include antifungals, immune modulators and anti-inflammatories to name just a few.

This comprehensive program, when applied cautiously, patiently, scientifically and systematically, has been clinically shown to trigger recoveries in children with each of the 4-A disorders. It appears as if this approach may represent one of the most promising avenues of treatment for autism, ADHD, asthma and allergies. Healing the environment and decreasing toxic exposures may ultimately be even more effective than medical treatment at stopping the proliferation of these new childhood epidemics. That task, though, will take time, and involve the cooperation of not only physicians, researchers and parents, but government and corporations as well.

For now, our focus must be on healing our children, one at a time. Our grave responsibility, as physicians and as parents, is to allow our children – born of love, and nurtured by those who love them most – to have the healthy, happy lives that all children deserve.

Photo Credit: Symic

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By Brendan Brazier on May 19, 2010

The Scoop on Omega-3

Recently I saw a generic brand of knock-off Oreo cookies. Not surprisingly, the first ingredient was refined sugar and the second was bleached, white flour. Across the front of the box, larger than the name of the cookies, it said: omega-3. That was the most prominent text! And while omega-3 is vastly important (essential even), the way its suggested usage is being promoted has become somewhat misguided. As with many healthy foods or nutrients grabbed by the mainstream, omega-3 consumption is slightly misunderstood.

An upswing in awareness of omega-3 began to develop soon after a World Health Organization (WHO) report was released. The report suggested that the average North American eats a diet with a vastly out-of-balance ratio of omega-6 to omega-3, which was linked to serious health problems. Consumers of the Standard American Diet (SAD) commonly ingest 20 times more omega-6 than omega-3. This was of great concern since the WHO determined in their extensive study that the ideal ratio for optimal health is 4:1, provided both sources of omega-6 and omega-3 are of high quality and in their natural, unrefined form.

Those eating a SAD were consuming five times more omega-6 than the ideal. A significantly out-of-balance ratio such as this was being blamed for a broad spectrum of ailments. Inflammation contributing to joint pain was one of the chief concerns, but the list was long and varied. Difficulty sleeping, general mental and physical fatigue, sugar cravings, the inability to burn body fat effectively, dry skin and even poor memory were all suspected of being a result of this off-kilter ratio. Serious implications indeed.

As a consumer-minded society we immediately concluded that these findings meant we should get more omega-3 in our diet to compensate for the lopsided ratio. Was this a bad approach? Not particularly, but it certainly wasn’t the most logical. Seemingly overnight omega-3 became a buzzword and everyone wanted to increase their omega-3 intake. Of course the next question was, “can I buy omega-3 supplements?” The answer very quickly became yes. This was a good thing, but it was far from optimal.

Another finding that emerged from the same WHO study was not as celebrated. The report also suggested that the problem was not merely created by too much omega-6 but rather by its sources. In addition to a distorted ratio, denatured, refined and highly processed forms of fat containing omega-6 were found to be part of the problem. Essentially eating too many high-temperature fried foods, denatured oils and manufactured fats (commonly used in cheaper baked goods to increase shelf life) was being blamed.

Taking into account the WHO’s findings on the ideal ratio, those of us who eat a diet that does not regularly contain large amounts of high-temperature fried foods, hydrogenated fats (such as those found in some margarines) or trans fats have no reason to use supplements with a greater ratio of omega-3 to omega-6. It’s just not necessary. If, however, a large part of your diet consists of denatured fats, fried foods and manufactured oils…stop eating them! Don’t just supplement your diet with omega-3 and think that you’ve solved the problem by balancing your ratio. It’s false hope and nothing more than a bandage that will offer a mild reprieve of symptoms at best. The cause will remain, and the problem will continue to worsen until it is addressed.

There are many highly corrective oil formulas on the market that offer 1:2 ratio of omega-6 to omega-3. Because of the reasons I’ve stated, I believe the best approach is to eat a healthy, balanced diet of whole foods as opposed to taking a highly corrective formula. A healthy diet includes balanced cold-pressed oils that yield a ratio between 4:1 and 2:1. I often make a salad dressing that combines cold-pressed, organic hemp seed oil (70%), flax seed oil (20%) and pumpkin seed oil (10%). Straight hemp oil is another good choice.

The WHO report concludes the best way to bring the ratio back to a healthy balance is to simply cut back on all processed, denatured and manufactured fats with a goal of complete elimination. Cold-pressed forms of omega-6 are perfectly healthy and essential to optimal health. As long as their quantity does not surpass four parts for every one part of omega-3, optimal health will be obtainable.

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